The SOX2 Antibody (C-term) from MyBioSource.com is a Rabbit Polyclonal antibody to lcc, SOX2, and SRY box 2. This antibody recognizes Human, and Mouse antigen. The SOX2 Antibody (C-term) has been validated for the following applications: ELISA, and Western Blot.
Description
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206 (By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal (By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation (By similarity)